Key result
A 53-year-old female with primary Ewing's sarcoma of the vulva showed resolution of iliac lymph nodes after four cycles of VAC/IE chemotherapy.
Why the study?
Extraskeletal Ewing's sarcoma presenting in the genitourinary tract is highly uncommon, with very few published cases of primary vulvar and vaginal disease to date.
Case Report (n=1)
No
Ewing's sarcoma of the vulva is a rare extraskeletal presentation that can be managed with surgical excision and multiagent chemotherapy.
Answers are grounded in this paper and cite their sources.
May support chemosensitivity in rare vulvar Ewing sarcoma; hypothesis-generating and requires prospective validation.
Extraskeletal Ewing's sarcoma (EES) is an uncommon, aggressive, round cell tumor. It accounts to 16% among Ewing's sarcoma (ES). The most commonly involved sites are soft tissues of trunk or lower extremities, paravertebral tissues, chest wall, and retroperitoneum. EES presenting in the genitourinary tract is highly uncommon. There are very few cases of primary vulvar and vaginal ES which have been published to date. We report a rare case of ES of the vulva that presented with labial swelling.
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Babu et al. (2020) conducted a case report in Ewing's sarcoma of the vulva (n=1). VAC/IE chemotherapy regimen was evaluated on Clinical response. A 53-year-old female with primary Ewing's sarcoma of the vulva showed resolution of iliac lymph nodes after four cycles of VAC/IE chemotherapy.
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