Key result
Trans-septal left atrial decompression using the Inoue balloon catheter was successfully performed in 14 of 15 adult patients on VA-ECMO, significantly reducing the oxygenation index from 9.9 to 4.6 (p<0.001).
Why the study?
Does percutaneous trans-septal left atrial decompression using an Inoue balloon catheter improve refractory pulmonary edema in adult patients on VA-ECMO?
Observational (n=15)
No
Does percutaneous trans-septal left atrial decompression using an Inoue balloon catheter improve refractory pulmonary edema in adult patients on VA-ECMO?
Trans-septal left atrial decompression using an Inoue balloon catheter is a feasible and safe method to rapidly resolve refractory pulmonary edema in adult patients on VA-ECMO.
May support Inoue balloon decompression for LA hypertension on VA-ECMO; leaves open confirmation of clinical benefit in prospective trials.
BACKGROUND: Refractory pulmonary edema is an infrequent but serious complication in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) for myocardial failure. Left atrial (LA) decompression in this setting is important. Although a few methods have been reported, the experience is mostly limited to children. We aimed to evaluate the feasibility of Inoue balloon catheter in percutaneous trans-septal LA decompression in adult cardiogenic patients. METHODS AND RESULTS: We retrospectively analyzed 16 procedures of trans-septal LA decompression by Inoue balloon catheter in 15 VA-ECMO patients (aged 22-65 years, 6 men) with refractory pulmonary edema from May 2012 to December 2014. Mean left ventricular ejection fraction was 15%. The cause of cardiogenic shock included 7 cases of ischemic heart disease, 1 of dilated cardiomyopathy, 5 of myocarditis, and 2 of fatal ventricular arrhythmia.The procedures were performed 4.3 days after ECMO. Inoue balloon size was 24-27 mm. LA septostomy were successfully created in 14 patients. Procedure time on average was 36.8 min (range, 15-85 min). There were no procedure-related complications.Radiography on the next day showed rapid resolution of pulmonary edema. CONCLUSIONS: Trans-septal LA decompression by Inoue balloon catheter is a feasible alternative method for adult patients with refractory pulmonary edema under ECMO.
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Lin et al. (2017) conducted an observational in Refractory pulmonary edema during VA-ECMO for myocardial failure (n=15). Trans-septal left atrial decompression by Inoue balloon catheter was evaluated on Procedural success (successful creation of an artificial atrial septal defect with full inflation of the Inoue balloon and left-to-right shunt). Trans-septal left atrial decompression using the Inoue balloon catheter was successfully performed in 14 of 15 adult patients on VA-ECMO, significantly reducing the oxygenation index from 9.9 to 4.6 (p<0.001).
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