Does inhibition of apolipoprotein B synthesis produce foie gras?

Q: What is the clinical evidence from this study?

Study design: Editorial. Population: Hyperlipidemia and familial hypercholesterolemia. Intervention: Inhibition of apolipoprotein B synthesis / Statin therapy. Primary outcome: LDL cholesterol reduction.

Q: What does this research mean for the field?

High doses of potent statins reduce LDL cholesterol by more than 50%, yet patients with familial hypercholesterolemia seldom achieve LDL cholesterol levels below 100 mg/dL on statin monotherapy alone. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Kenneth R. Feingold

doi:10.1194/jlr.e005140

December 31, 2009Journal of Lipid ResearchOpen Access

Does inhibition of apolipoprotein B synthesis produce foie gras?

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PICO

P

Population

Hyperlipidemia and familial hypercholesterolemia

I

Intervention / Comparator

Inhibition of apolipoprotein B synthesis / Statin therapy

O

Primary Outcome

LDL cholesterol reduction

Abstract

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Cite This Study

Kenneth R. Feingold (2009) conducted an editorial in Hyperlipidemia and familial hypercholesterolemia. Inhibition of apolipoprotein B synthesis / Statin therapy was evaluated on LDL cholesterol reduction.

synapsesocial.com/papers/6a71c68631a3df824329ce82 https://doi.org/10.1194/jlr.e005140

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Does inhibition of apolipoprotein B synthesis produce foie gras?

PICO

Abstract

Discussion

Cite This Study

Does inhibition of apolipoprotein B synthesis produce foie gras?

PICO

Abstract

Discussion

Cite This Study

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