Key result
Mental stress elicited highly variable renal and muscle sympathetic responses, with individuals exhibiting negative responses displaying lower blood pressure reactivity than positive responders.
Why the study?
How do renal vascular resistance and muscle sympathetic nerve activity respond to mental stress, and how do these responses affect blood pressure reactivity?
Observational
How do renal vascular resistance and muscle sympathetic nerve activity respond to mental stress, and how do these responses affect blood pressure reactivity?
There is significant interindividual variability in sympathetic and vascular responses to mental stress, which integratively contribute to blood pressure regulation.
Interindividual variability in sympathetic stress responses may modulate BP reactivity; hypothesis-generating for personalized risk stratification.
We found large interindividual variability in renal vascular resistance (RVR) and muscle sympathetic nerve activity (MSNA) responses to mental stress, with only 52% of participants exhibiting concordant response patterns. Individuals with typically negative responses (i.e., decreases in RVR and MSNA, or decreases in one and no changes in the other) displayed lower blood pressure reactivity than typically positive responders, highlighting the integrative contribution of renal and muscle vasoconstriction on blood pressure regulation during mental stress.
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Teixeira et al. (2025) reported an observational. Mental stress vs. Typically positive responders was evaluated on Blood pressure reactivity. Mental stress elicited highly variable renal and muscle sympathetic responses, with individuals exhibiting negative responses displaying lower blood pressure reactivity than positive responders.
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