Key result
Perioperative blood pressure variability was significantly associated with the occurrence of cerebral hyperperfusion syndrome, which developed in 4.8% of patients (P<0.05).
Why the study?
To investigate the effect of perioperative blood pressure variability on cerebral hyperperfusion syndrome after carotid artery stenting.
Does perioperative blood pressure variability increase the risk of cerebral hyperperfusion syndrome in patients undergoing carotid artery stenting?
Observational (n=418)
No
Does perioperative blood pressure variability increase the risk of cerebral hyperperfusion syndrome in patients undergoing carotid artery stenting?
p-value: p=<0.05
Perioperative blood pressure variability is associated with an increased risk of cerebral hyperperfusion syndrome after carotid artery stenting.
BP variability was associated with post-CAS CHS; hypothesis-generating, prospective trials needed before practice change.
Objective To investigate the effect of perioperative blood pressure variability on cerebral hyperperfusion syndrome after carotid artery stenting. Methods A retrospective analysis was conducted of data collected from 418 patients who underwent carotid artery stenting in Guangxi Zhuang Autonomous Region People's Hospital in China. The blood pressure data were collected during operation (after balloon dilation, before stent release, after stent release) and within 3 days after the operation. The blood pressure variability was evaluated by measuring the mean, maximum, minimum, max–min, standard deviation (SD) of systolic blood pressure (SBP) and diastolic blood pressure (DBP). The correlation between blood pressure variability and cerebral hyperperfusion syndrome was analysed. Results Blood pressure data from 418 patients were analysed. Twenty patients (4.8%) developed cerebral hyperperfusion syndrome. The parameters of blood pressure variability were divided into four groups according to quartile. After adjusting for age, symptomatic carotid stenosis, unilateral carotid stenosis, bilateral carotid stenosis, collateral circulation, diabetes mellitus and chronic kidney disease, multivariate analysis showed that SBP Max , SBP Min , SBP Max−Min , SBP CV , DBP SD , DBP Max , DBP Min , DBP Max−Min and DBP CV were associated with the occurrence of cerebral hyperperfusion syndrome ( P < 0.05), respectively. Conclusion This study suggests that blood pressure variability during the perioperative period may increase the risk of cerebral hyperperfusion syndrome.
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Guo-yong et al. (2021) conducted an observational in Carotid artery stenting (n=418). Perioperative blood pressure variability was evaluated on Cerebral hyperperfusion syndrome (p=<0.05). Perioperative blood pressure variability was significantly associated with the occurrence of cerebral hyperperfusion syndrome, which developed in 4.8% of patients (P<0.05).
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