Why the study?
Does long-term anticoagulant treatment improve survival or reduce recurrent stroke in patients with non-rheumatic atrial fibrillation and cerebral infarction?
Population
120 patients with non-rheumatic atrial fibrillation and cerebral infarction (stroke)
Comparison
Long-term anticoagulant treatment vs No anticoagulants
Design
Cohort
Follow-up
mean 27 months
Authors
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No survival or recurrent stroke benefit seen with long-term anticoagulation; leaves open efficacy pending randomized trials in non-rheumatic AF.
Does long-term anticoagulant treatment improve survival or reduce recurrent stroke in patients with non-rheumatic atrial fibrillation and cerebral infarction?
In this observational cohort comparison, long-term anticoagulation did not significantly improve survival or reduce recurrent stroke in patients with non-rheumatic atrial fibrillation and prior cerebral infarction.
Lodder et al. (1988) studied this question.
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