March 26, 2008Journal of Cardiovascular Electrophysiology
Age‐ and Genotype‐Specific Triggers for Life‐Threatening Arrhythmia in the Genotyped Long QT Syndrome
Population
145 symptomatic genotyped long QT syndrome patients, divided by age of first symptom onset
Design
Cohort
Authors
Discussion
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Member takes
Implication
May warrant age-specific trigger assessment in LQTS; leaves open impact on outcomes.
Structured PICO
P
Population
145 symptomatic genotyped long QT syndrome (LQTS) patients, divided by age of first symptom onset (young <20, intermediate 20-39, older ≥40 years)
O
Outcome
Triggers of cardiac events (ventricular tachycardia, syncope, or cardiac arrest)hard clinical
Arrhythmic triggers in long QT syndrome differ significantly by age of onset, with secondary triggers like drugs and hypokalemia being predominant in older patients, highlighting the need for age-specific management.
Cite This Study
Sakaguchi et al. (2008) studied this question.