Key result
Molecular analysis of enterovirus A71 infections in Germany in 2019 showed co-circulation of sub-genogroups C1 and C4 among hospitalized patients with suspected aseptic meningitis/encephalitis.
Observational
Highlights the co-circulation of EV-A71 sub-genogroups C1 and C4 in Germany in 2019, prompting intensified diagnostic efforts for patients with neurological symptoms.
Warrants ongoing EV-A71 surveillance across Europe; leaves open sub-genogroup differences in neurovirulence.
We report on the increased circulation of enterovirus A71 in Germany in 2019. Strains were mainly identified in hospitalised patients with suspected aseptic meningitis/encephalitis. Molecular analysis showed co-circulation of EV-A71 sub-genogroups C1 and C4, a signal for physicians and public health authorities to include/intensify EV diagnostic in patients showing signs of aseptic meningitis, encephalitis or acute flaccid paralysis/myelitis.
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Böttcher et al. (2019) conducted an observational in enterovirus A71 infections. enterovirus A71 infection was evaluated on co-circulation of EV-A71 sub-genogroups C1 and C4. Molecular analysis of enterovirus A71 infections in Germany in 2019 showed co-circulation of sub-genogroups C1 and C4 among hospitalized patients with suspected aseptic meningitis/encephalitis.
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