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Those interested in antimicrobial agents and chemotherapy culture microorganisms for a variety of tests. These include susceptibility assessments, bioassays, studies of the interactions between antibiotics and host defenses, and in vitro stimulation of in vivo conditions for purposes of extrapolation. The specific physiological state of the organisms used, especially surface properties, greatly influences the outcome of all such tests.
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Brown et al. (1990) studied this question.
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