In spontaneous diabetes of man and some laboratory animals and in experimental diabetes of rats hepatic enzyme activities of glycolysis (glucokinase, hexokinase, phosphofructokinase, pyruvatekinase) and gluconeogenesis (glucose-6-phosphatase, fructose-diphosphatase) were studied. Aldolase was also assayed as example of a bifunctional enzyme.
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Willms et al. (1970) studied this question.
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