A Case of Angiosarcoma of the Breast

A 64-year-old female was admitted to the hospital because of a left breast lymp. A movable and 2×2cm elastic soft tumor was palpable in the left breast. US showed that the margin was clear, the edge was smooth, and L/D was samll. There was a shadow like frosted glass in mammography. She underwent incisional breast biopsy and the specimen revealed angiosarcoma. Simple mastectomy was performed after comfirmation of no metastasis; after about two months from her first visit. 400, 000 unit IL-2 was administered i.v. everyday for three weeks from 4th post operative day (pod) as adjuvant chemotherapy. She was discharged at 26th pod and for the present there has been no signs of recurrence. Angiosarcoma of the breast is a rare disease entity and the prognosis is remarkably poor. The 5-year suvival rate is 0% in the 22 cases seen in the Japanese literature. The patients almost die of blood-borne metastasis, but lymphatic metastasis rarely occurs. The only way to make the patient survive is to diagnose earlir and to perform operation while the tumor is still small in size. We report a patient with angiosarcoma of the breast who is expected a long survival.