This case series describes the heterogeneous histopathologic features and variable clinical outcomes of breast angiosarcoma.
Variable short-term outcomes in rare breast angiosarcoma warrant cautious counseling; leaves open optimal therapy pending larger studies.
The histopathologic and clinical features of 3 breast angiosarcomas were presented. The microscopic patterns were heterogeneous, comprising vascular structures in various degrees of differentiation and solid cellular proliferations, the proportion of which varied from tumor to tumor. All 3 tumors were classified in the third group of angiosarcomas. One widely-excised tumor recurred and developed lung metastases 11 months after mastectomy and during a polychemotherapy. The other 2 patients were well and free from disease 9/11 months after the surgical and radiation therapy.
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Gadaleanu et al. (1987) studied this question.
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