Why the study?
Is postoperative confusion in schizophrenic patients associated with an increased norepinephrine and cortisol response to surgery?
Population
85 patients (50 schizophrenic patients and 35 control patients) who underwent orthopedic surgery
Design
Cohort
Follow-up
72 hours
Authors
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May warrant closer monitoring for confusion in schizophrenic surgical patients; hypothesis-generating for stress-hormone modulation.
Is postoperative confusion in schizophrenic patients associated with an increased norepinephrine and cortisol response to surgery?
Postoperative confusion in schizophrenic patients undergoing orthopedic surgery is associated with an exaggerated stress hormone response, specifically elevated norepinephrine and cortisol levels.
Kudoh et al. (2002) studied this question.
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