Leading antioxidant remedies for the management of male reproductive dysfunction – A review

Oxidative stress stemming from distortions in the balance between reactive oxygen species (ROS) and antioxidants, plays a leading role in the pathophysiology of male reproductive dysfunction. A convincing body of evidence emphasizes on the importance of oral antioxidant therapy in the management of male sub- or infertility. As such, the focus of this review is to present recent evidence assessing the in vivo effects of conventional and traditional antioxidant remedies on male reproductive function with a special emphasis on oral delivery of the substance and rats as the leading animal model in biology and medicine.