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Transcranial Doppler-measured vasomotor reserve is a useful tool for evaluating cerebral microcirculation and autoregulation in conditions like carotid stenosis.
In this week's WriteClick, Dr. Shang and authors Silvestrini et al. discuss the role of transcranial Doppler (TCD)-measured vasomotor reserve (VMR) in studying carotid stenosis and cerebral microcirculation.VMR evaluates the compensatory response of the cerebral small vessels (autoregulation) to a stimulus.Carbon dioxide or acetazolamide is used to stimulate vasodilation and then VMR is calculated from the measured change in blood velocity.Vessels already dilated from decreased perfusion pressure due to carotid stenosis have less capacity to react.VMR has been used to analyze syncope, predict autonomic dysfunction in Parkinson disease, and study circulation and autoregulation in migraine with aura, Alzheimer disease, and even altitude sickness.
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Ty Shang (2013) studied this question.
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