Why the study?
Does the heart rate response to the Valsalva maneuver differ in diabetics compared to matched controls and correlate with autonomic neuropathy?
Does the heart rate response to the Valsalva maneuver differ in diabetics compared to matched controls and correlate with autonomic neuropathy?
Monitoring heart rate changes during the Valsalva maneuver is a simple and effective method for assessing autonomic neuropathy in diabetic patients.
Supports Valsalva testing for autonomic neuropathy detection in diabetes; hypothesis-generating and should not yet change screening practice.
Changes in heart rate on performing the Valsalva maneuver can easily be monitored with an EKG and a modified sphygmomanometer. Observations have been made on twenty-four diabetics and their matched controls. Impairment of cardiovascular reflexes demonstrated by this technic correlates well with the presence of other complications of diabetes, especially neuropathy. Impairment of response increases exponentially with duration of the disease but not with age. Assessment of the degree of autonomic nervous involvement in diabetic patients is of assistance in their management. The procedure employed has proved satisfactory in gaining necessary information rapidly with easily available apparatus.
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Nathanielsz et al. (1967) studied this question.
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