P474: Precision child health: Integrating a consultative pharmacogenetics (PGx) program into clinical care at the Hospital for Sick Children*

Pharmacogenetics (PGx) may identify inter-individual variability influencing drug response, efficacy, and the occurrence of adverse drug events and is a cornerstone of precision medicine. Despite these advantages, clinical integration of PGx faces challenges stemming from a lack of awareness and guidance. To address this, we introduce the establishment of a consultative PGx program within the Division of Clinical Pharmacology & Toxicology at The Hospital for Sick Children (SickKids). The clinic advises healthcare professionals on how to integrate PGx data into their daily clinical practice, thus increasing medication safety.