Recurrent ATM mutations in T-PLL on diverse haplotypes: no support for their germline origin

The ATM gene has been found to be mutated or deleted in the majority of cases of T cell prolymphocytic leukemia (T-PLL),[1-5][1] and missense mutations were shown to cluster in the highly conserved gene region encoding the ATM kinase domain.[1][1] Recently, Vanasse et al reported that as many as