It is shown from a combination of rapid quenching and steady-state kinetics that the phenylalanyl-tRNA synthetase from yeast catalyses the formation of phenylalanyl-tRNA by the amino-acyladenylate pathway at pH 7.8 and 25 degrees C. The rate-determining step at saturating reagent concentrations is not the dissociation of the charged tRNA from the enzyme.
No takes yet. Share an insight, caveat, or question.
Fasiolo et al. (1978) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: