Why the study?
Coexisting conditions may prohibit invasive catheter ablation for recurrent VT, and the mechanisms and timing of antiarrhythmic effects of noninvasive cardiac radioablation remain incompletely understood.
Does cardiac radioablation improve clinical outcomes in a patient with therapy-refractory ventricular tachycardia storm?
Does cardiac radioablation improve clinical outcomes in a patient with therapy-refractory ventricular tachycardia storm?
Cardiac radioablation may serve as a noninvasive treatment option for patients with therapy-refractory ventricular tachycardia storm who cannot undergo invasive catheter ablation.
Patients with recurrent ventricular tachycardia (VT) are treated with antiarrhythmic drugs and invasive catheter ablation(s).1 Unfortunately, though some patients have an (urgent) indication for invasive catheter ablation, coexisting conditions may prohibit such procedures. Cardiac radioablation, or stereotactic arrhythmia radiation therapy, is a new and promising noninvasive treatment modality for patients considered therapy-refractory or untreatable.2 Although the mechanism of action of cardiac radioablation remains to be elucidated, based on previous data the antiarrhythmic effects of cardiac radioablation could take several weeks to several months.
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Ree et al. (2022) studied this question.
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