Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1974Scandinavian Journal of Clinical and Laboratory Investigation

Muscle ATP Content in Rheumatoid Arthritis - a Biopsy Study

View Full Paper
Ask AI
Bookmark
Share

Population

Patients with rheumatoid arthritis (RA)

Comparison

Muscle biopsy vs Normal healthy subjects and patients with…

Design

Case-control

Authors

RNR. NordemarSaint Göran HospitalOLO LövgrenS:t Eriks ÖgonsjukhusPFP. FürstUniversity of Bern

Discussion

Loading...

Member takes

Implication

Lower muscle ATP in RA may relate to symptoms or duration; hypothesis-generating and should not yet change practice.

Structured PICO

P
Population
Patients with rheumatoid arthritis (RA)
I
Intervention
Muscle biopsy
C
Comparator
Normal healthy subjects and patients with connective tissue diseases other than RA
O
Outcome
Muscle ATP levelssurrogate

Rheumatoid arthritis is associated with significantly lower muscle ATP content compared to healthy controls and other connective tissue diseases, which appears related to disease duration.

Cite This Study

Nordemar et al. (1974) studied this question.

synapsesocial.com/papers/6a722acea7fbea1e44089bf8https://doi.org/10.1080/00365517409050833
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Differential Changes in Type I And Type Ii Muscle Fibres in Rheumatoid Arthritis: A Biopsy Study1974 · 62 citations
  2. 2Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients2020 · 8 citations
  3. 3Peripheral blood mononuclear cells show markers of mitochondrial dysfunction in rheumatoid arthritis2024 · 12 citations
  4. 4Inflammation, mitochondrial and lysosomal dysfunction as key players in rheumatoid arthritis?2024 · 5 citations
  5. 5JAK inhibitors improve ATP production and mitochondrial function in rheumatoid arthritis: a pilot study2023 · 13 citations