Bleeding is the one of leading cause of death after civil and combat trauma and affective hemostasis is a key challenge for emergency medicine. Current review focused on modern topical hemostatic agents based on chitosan. This article prescribes mechanism of action of chitosan and its interaction with blood plasma, erythrocytes and platelets. Review classified all topical hemostatic agents and show advantage of chitosan-based dressind. Also it gives perspectives in hemostatic dressing research.
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Pogorielov et al. (2015) studied this question.
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