Key result
Coumarins from Zanthoxylum schinifolium root bark demonstrate in vitro antiplatelet aggregation activity.
Further study on the chloroform-soluble portion of the root bark of Zanthoxylum schinifolium led to the isolation of eight new coumarins: methylschinilenol (1), hydroxyepoxycollinin I (2), 8-methoxyanisocoumarin H (3), hydroxyschininallylol (4), hydroxyepoxycollinin II (5), schinitrienin (6), schininallylone (7), and isoschinilenol (8), along with twenty-six known compounds including fourteen coumarins, and nine alkaloids. The structural elucidation was determined by spectroscopic data. Among the isolates, terpenyl-coumarins and furoquinolines were the active constituents with antiplatelet aggregation in vitro and collinin (10) showed significant anti-HBC DNA replication activity.
No takes yet. Share an insight, caveat, or question.
Tsai et al. (2000) studied this question. Zanthoxylum schinifolium root bark isolates (terpenyl-coumarins, furoquinolines, and collinin) was evaluated on In vitro antiplatelet aggregation and anti-HBC DNA replication activity. Eight new coumarins and 26 known compounds isolated from Zanthoxylum schinifolium root bark demonstrated in vitro antiplatelet aggregation and anti-HBC DNA replication activity.
Synapse has enriched 5 related papers. Consider them for comparative context: