The Siddha system is one of the traditional systems which provide healthy life to humans through the natural sources in the form of herbals, minerals and animal products. Lavaņa kuḻambu is a Siddha herbo-mineral formulation mentioned in the Siddha text Aņupõka Vaittiyanavaṉītam. Kuḻambu is a semi solid preparation with the shelf life of 5 years. The drug is indicated for Pīlīkai kaṭṭi, Kavitai kaṭṭi, Pāņṭu, Kāmālai, Peruvayiṟu, Makōtaram All these symptoms are related to the dysfunction of the vital organ Liver. Liver inflammation and oxidative stress are commonly associated with development and progression of chronic liver disease. It is evident that the natural products with anti inflammatory and anti oxidant activities posses therapeutic effect against inflammation, fibrosis and metabolic disorders. This review is aimed to bring out scientific evidence for the therapeutic usage of Lavaņa kuḻambu and focused on the Hepato protective activity for the curative nature of the drug. It is unambiguous that the ingredients in the Lavaņa kuḻambu have Hepato protective activity as per the Siddha literature and scientific evidence.
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Swathi et al. (2024) studied this question.
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