Article1 September 1930Undulant Fever (Brucelliasis)A Clinicopathologio Study of Ninety Cases Ocurring in and About Dayton, OhioWALTER M. SIMPSON, M.S., M.D., F.A.C.P.WALTER M. SIMPSON, M.S., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-4-3-238 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUndulant fever is now recognized as a common disease of man. The knowledge of its widespread distribution, particularly in this country, is largely a development of the past two years. At a recent meeting of the Health Section of the League of Nations, it was stated that undulant fever is the most important problem facing public health workers at the present time. Prior to 1925, 128 cases of undulant fever had been recorded in this country. During the period from 1925 to 1928, the recorded cases numbered 24, 46, and 217 respectively; during 1928, largely due to the dissemination of...References1 HARDY AVData obtained from . Google Scholar2 SIMPSONFRAIZER WME: Undulant Fever: Report of Sixty-Three Cases Occuring in and about Dayton, Ohio. J.A.M.A., 1929, 93, 1958-1963. CrossrefGoogle Scholar3 HARDY AV: Undulant Fever: Etiology, Epidemiology and Laboratory Diagnosis. J.A.M.A., 1929, 93, 891-897. CrossrefGoogle Scholar4 CARPENTERKING CMMJ: Brucella abortus in Milk and its Relation to Undulant Fever. Am. Pub. Health A., Symposium on Undulant Fever, 1929, 1-11. Google Scholar5 HUDDLESON IF: Is Bacterium abortus Pathogenic for Human Beings? J.A.M.A., 1926, 86, 943-944; Undulant Fever in Man and its Relation to Bovine Infectious Abortion (Bang's Abortion Disease). J. Mich. State Med. S., 1927, 26, 664-666; ORR, P. F. and HUDDLESON, I. F.: A Further Epidemiological Study of Undulant Fever in Michigan. Am. Pub. Health A., Symposium on Undulant Fever, 1929, 34-38. CrossrefGoogle Scholar6 KING MJ: Brucella abortus Infection of Milk. N.E.J. Med., 1929, 201, 918-922. Google Scholar7 BIERRING WL: Undulant Fever: Clinical Characteristics Based on a Study of One Hundred and Fifty Cases Observed in Iowa. J.A.M.A., 1929, 93, 897-901. CrossrefGoogle Scholar8 FARBARMATHEWS MEFP: An Epidemic of Undulant Fever. Ann. Int. Med., 1929, 2, 875. LinkGoogle Scholar9 BROWN EG: Undulant Fever: Report of 62 Cases Occurring in Kansas. Bull. Kansas State Board of Health, September, 1929. Google Scholar10 SENSENICHGIORDANO RLAS: Brucella abortus Infection in Man: Report of Seven Cases. J.A.M.A., 1928, 90, 1782. GIORDANO, A. S., and ABLESON, M.: Brucella abortus Infection in Man: A Serologic Study. J.A.M.A., 1929, 92 198; GIORDANO, A. S. and SENSENICH, R. L.: Brucella abortus Infection in Mans A Clinical Analysis of Thirty-Five Cases. J. Lab. and Clin. Med., 1930, 51, 421-436. CrossrefGoogle Scholar11 EY LF: Undulant Fever in Ohio. Ohio State Med. J., 1930, 26, 225-230. Google Scholar12 EVANS AC: Further Studies of Bacterium abortus and Related Bacteria. J Infect. Dis., 1918, 22, 580. CrossrefGoogle Scholar13 EVANS AC: Experimental Abortion in a Cow Produced by Inoculation with Bacterium melitensis. Pub. Health Rep., 1923, 38, 825. CrossrefMedlineGoogle Scholar14 FLEISCHNERVECKISHAWMEYER ECMEBKF: The Pathogenicity of B. abortus and B. Melitensis for Monkeys. J. Infect. Dis., 1921, 29, 663-698. CrossrefGoogle Scholar15 CARPENTER CM: Results of Injecting Pregnant Heifers with Brucella abortus Isolated from Man. J.A. Vet. M.A., 1927, 70, 459-468. Google Scholar16 MEYERSHAW KFEB: A Comparison of the Morphologic, Cultural and Biochemical Characteristics of B. abortus and B. melitensis. J. Infect Dis., 1920, 27, 173-184. CrossrefGoogle Scholar17 FITCH CP: Control of Abortion Disease. Vet. Alumni Quart., Ohio State U., 1919, 17, 119-127. Google Scholar18 HARDYHUDSONJORDAN AVMGCF: The Skin as a Portal of Entry in Br. melitensis Infections. J. Infect. Dis., 1929, 45, 271-282. CrossrefGoogle Scholar19 MCALPINEMICKLE JGFL: Bacterium abortus Infection in Man: Results of Agglutination Test Applied to more than 10,000 Human Sera. Am. J. Pub. Health, 1928, 18, 609-613. CrossrefGoogle Scholar20 KERN RA: The Clinical Aspects of Brucella melitensis variety abortus Infection in Man. Am. J.M. Sc., 1928, 176, 405. CrossrefGoogle Scholar21 HIRSCHBOECK FJ: Undulant Fever. Minn. Med., 1929, 12, 590. Google Scholar22 HADLEYBARNESHALLMANFITCHLOTHE FBMFETCPH Report of Committee on Abortion., Am. Vet. Med. A., (). J.A. Vet. M.A., 1928, 73, 765-767. Google Scholar23 SCHROEDERCOTTON ECWE: An Undescribed Pathogenic Bacterium in Milk. Proc. Am. Vet. M. A., 1911, p. 442; The Bacillus of Infectious Abortion Found in Milk. 28th Ann. Rep. Bureau Animal Indus., U. S. Dept. Agriculture, 1911, pp. 139-146. Google Scholar24 CARPENTER CM: Brucella abortus in Udders of Vaccinated and Naturally Infected Cattle. Cornell Vet., 1926, 61, 133. Google Scholar25 FLEISCHNERMEYER ECKF: Presence of Bacillus abortus-bovinus in Certified Milk. Am. J. Dis. Child., 1917, 14, 157. CrossrefGoogle Scholar26 Peters WHPersonal communication to author from , Health Commissioner, Cincinnati, Ohio. Google Scholar27 KOHLBRY CO: Undulant Fever in Infant. Minn. Med., 1912, 12, 414. Google Scholar28 MOORECARPENTER VACM: Undulant Fever in Man Associated with Bacteria Indistinguishable from Brucella abortus. Cornell Vet., April, 1926, p. 150. Google Scholar29 SCOTTSAPHIR RWO: Brucella melitensis (abortus) Bacteremia Associated with Endocarditis. Am. J. M. Sc., 1928, 175, 66. CrossrefGoogle Scholar30 DE LA CHAPELLE CE: Vegetative Endocarditis due to Brucella melitensis. Am. Heart J., 1929, 4, 732-739; Endocarditis in Malta Fever (Undulant Fever). Arch. Path., 1929, 7, 932. CrossrefGoogle Scholar31 AMOSSBOSTON HLMA: Undulant (Malta) Fever: Isolation of the Brucella Organism from the Stools. J.A.M.A., 1929, 93, 170. CrossrefGoogle Scholar32 SIMPSONBOWERS WMLG: Surgical Aspects of Undulant Fever. Am. J. Surg., 1929, 7, 597-604. CrossrefGoogle Scholar33 DE FOREST HP: Infectious Abortion of Cattle as a Complication of Pregnancy in Women. Am. J. Obstet. and Dis. Women and Children 1917, 76, 221-254. LARSON, W. P. and SEDGWICK, J. P.: The Complement Fixation Reaction of the Blood of Children and Infants, Using the Bacillus abortus as Antigen. Am. J. Dis. Child., 1913, 6, 326-333; SEDGWICK, J. P. and LARSON, W. P.: Further Studies on the Epidemic Abortion Reactions in Children. Am. J. Dis. Child., 1915, 10, 197-200. Google Scholar34 CARPENTERBOAKCHAPMAN CMROD: The Significance of Brucella Abortus Agglutinins in Human Serum. J. Immunol., 1929, 17, 65. Google Scholar35 Carpenter CMPersonal communication from to the author. Google Scholar36 HUDDLESONHALLMAN IFET: The Pathogenicity of the Species of the Genus Brucella for Monkeys. J. Inf. Dis., 1929, 45, 293-303. CrossrefGoogle Scholar37 EVANS AC: Studies on Brucella (Alkaligenes) melitensis. Hyg. Lab. Bull., 143, 1925, p. 2. Google Scholar38 HUDDULESJNABELL IFE: Rapid Macroscopic Agglutination for the Serum Diagnosis of Bang's Abortion Disease. J. Inf. Dis., 1928, 42, 242-247. CrossrefGoogle Scholar39 SIMPSON WM: Tularemia (Fancis' Disease): A Clinical and Pathological Study of Forty-Eight Non-Fatal Cases and One Rapidly Fatal Case with Autopsy, Occurring in Dayton, Ohio. Ann. Int. Med., 1928, 1, 1007-1060; Tularemia (Francis' Disease): Report of Four Additional Cases. Ohio State M. J., 1928, 24, 860-862; Recent Developments in Tularemia (Francis' Disease); with a Report of Eleven Additional Cases. J. Lab. and Clin. Med., 1930, 15, 311-322; Tularemia, 8vo. cloth book, Paul B. Hoeber, Inc., New York, 1929. LinkGoogle Scholar40 BURNET E: Diagnostic de la fièvre Méditerranée par intradermoreaction: Action du filtrat de culture du M. melitensis, Arch. d'Inst. Pasteur de l'Afrique du Nord. 1922, 2, 187; Essais de diagnostic de l'infection a M. melitensis chez la chèvre par inoculation de molitine. Arch. de l'Inst. Pasteur de Tunis, 1924, 13, 1. Google Scholar41 MITRA M: La Intradermoreazione nella febbre Mediterranea dell'infanzia. Pediatria, 1924, 32, 721. Google Scholar42 BUA F: Sul metodo ed il valore dellintradermoreazione nella melitense. Minerva med., 1926, 6, 394. Google Scholar43 TRENTI E: Il valore della intradermoreazione nell'infezione melitense. Policlinico, 1925, 32, 767. Google Scholar44 FLEISCHNERMEYERSHAW ECKFEB: A Résumé on some Experimental Studies on Cutaneous Hypersensitiveness. Am. J. Dis. Children, 1919, 18, 577-590. Google Scholar45 GIORDANO AS: Brucella abortus Infection in Man: The Intradermal Reaction as an Aid in Diagnosis. J.A.M.A., 1929, 93, 1957. CrossrefGoogle Scholar46 GILTNER W: The Present Status of Infectious Abortion Control from the Laboratory Standpoint. J.A. Vet. M.A., 1929, 74, 880-884. Google Scholar47 ZWICKWEDEMAN .: Cited by BOAK and CARPENTER, J. Inf. Dis., 1928, 43, 327-329. CrossrefGoogle Scholar48 PARK WH: Personal communication to the author. Google Scholar49 PARK WH: Personal communication Therman Death Point of .Brucella abortus in Milk. J. Inf. Dis., 1928, 43, 327-329. CrossrefGoogle Scholar50 ROSSMARTIN GRAP: The Treatment of Undulant Fever by Mercurochrome―220. J. Trop. Med. and Hyg., 1927, 30, 165-170. Google Scholar51 BASSETT-SMITH PW: Undulant Fever. J. Trop. M. and Hyg., 1921, 24, 173-176. Google Scholar52 AURICCHIO L, Cited by EVANS, A. C.: Studies on Brucella (Alkaligenes) melitensis. Hyg. Lab. Bull. 143, p. 3. Google Scholar53 ANGLE FE: The Treatment of Undulant Fever with Vaccine. J. Kansas M. Soc., 1929, 30, 323. Google Scholar54 HELWIG FC: Undulant Fever. J. Mo. M. A., 1929, 26, 449. Google Scholar55 CUMSTON GC: The Treatment of Malta Fever. Med. J. and Rec., 1925, 121, 219. Google Scholar56 DE FINIS G: L'immunoterapia dei tifo, dei paratifi a della febbre mediterranea con i vaccini lisizzati di Cristina e Caronia. Pediatria, 1923, 31, 11-23. Google Scholar57 GUIFFRE M: Osservationi sulla vaccinoterapia nella febbre mediterranea. Pediatria, 1927, 35, 345-358. Google Scholar58 KHALED Z, Cited by EVANS, A. C.: Studies on Brucella (Alkaligenes) melitensis. Hyg. Lab. Bull. 143, p. 3. Google Scholar59 PRAUSNITZ C: Infektionen des Menschen durch des Bacterium Abortus Bang. Med. Klin., 1929, 25, 135-137. Google Scholar60 NICOLLECONSEIL CE: Vaccinations préventives par voie digestiv chez l'homme dans la dystenterie bacillaire et la fièvre méditerraneanne. Ann. de l'Inst. Pasteur, 1922, 36, 579-613. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *From the Diagnostic Laboratories of the Miami Valley Hospital, Dayton, Ohio.†Presented, in part, before the Fourteenth Annual Clinical Session of the American College of Physicians, Minneapolis, February 13, 1930. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPathology of selected infectious diseasesAn unsuspected case of brucellosis mimicking appendicitis in a child A chronology of laboratory and clinical findings and laboratory precautionsBrucellosis and Heart DiseaseBRUCELLA SENSITIZATION: A CLINICAL EVALUATION*WARD DARLEY, M.D., F.A.C.P., R. W. GORDON, M.D., F.A.C.P.The Diagnosis and Treatment of BrucellosisOrchitis as a complication of brucellosis (undulant fever)Brucellosis (Undulant Fever, Malta Fever, Bang’s Disease, Infectious Abortion of Domestic Animals)Brucella spondylitisTHE CLINICAL MANIFESTATIONS AND DIAGNOSIS OF CHRONIC BRUCELLOSIS*ROBERT C. MANCHESTER, M.S., M.D.THE DIAGNOSIS AND MANAGEMENT OF BRUCELLOSIS*WALTER M. SIMPSON, M.S., M.D., F.A.C.P.Orchitis and Epididymitis Due to Undulant FeverStudies of Correlated Human and Bovine Brucelliasis —Statistical and SerologicalUndulant Fever: A Fatal Case*†R. C. ROTHENBERG, M.D.The Incidence of Undulant Fever in Children 1 September 1930Volume 4, Issue 3Page: 238-259KeywordsFeversPrevention, policy, and public health ePublished: 1 December 2008 Issue Published: 1 September 1930 PDF downloadLoading ...
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