Key result
Second-generation antipsychotics like clozapine and olanzapine induce metabolic disturbances and lipid biosynthesis, contributing to increased cardiovascular mortality in schizophrenia.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Skrede et al. (2012) conducted an editorial in Schizophrenia and psychotic disorders. Second-generation antipsychotics (clozapine and olanzapine) was evaluated on Metabolic disturbances (obesity, hypertriglyceridemia, glucose dysregulation, elevated serum cholesterol) and cardiovascular mortality. Second-generation antipsychotics like clozapine and olanzapine induce metabolic disturbances and lipid biosynthesis, contributing to increased cardiovascular mortality in schizophrenia.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: