November 24, 2022VirusesOpen Access

African Swine Fever Modified Live Vaccine Candidates: Transitioning from Discovery to Product Development through Harmonized Standards and Guidelines

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Why the study?

A major impediment to accelerating African Swine Fever vaccine candidates into regulatory development is the absence of internationally harmonized standards for assessing purity, potency, safety, and efficacy.

Design

Review

Authors

DBDavid A. BrakeAdelson Foundation

Discussion

Member takes

Implication

May spur ASF vaccine R&D investment; leaves open optimal gene-deleted MLV candidates for licensure.

Structured PICO

Population

African Swine Fever (ASF) modified live virus (MLV) vaccine candidates in preclinical or early feasibility studies

Intervention

African Swine Fever (ASF) modified live virus (MLV) first-generation gene deleted vaccine candidates

The establishment of harmonized international guidelines by the World Organisation for Animal Health is paramount for the successful regulatory development and approval of ASF MLV vaccines.

Cite This Study

David A. Brake (2022) studied this question.

synapsesocial.com/papers/6a7239ae35aa2c282ce325a0 https://doi.org/10.3390/v14122619

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African Swine Fever Modified Live Vaccine Candidates: Transitioning from Discovery to Product Development through Harmonized Standards and Guidelines

Discussion

Member takes

Implication

Structured PICO

Cite This Study

African Swine Fever Modified Live Vaccine Candidates: Transitioning from Discovery to Product Development through Harmonized Standards and Guidelines

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider