Electrical potential measurements indicated that the absorption of salt across the small intestine was the result of active transport of Na + , followed passively by an equivalent of Cl – . The potential across the intestine was positive on the serosal side and higher in the jejunum than in the ileum. The Na + concentration in the bathing media determined the magnitude of the potential; other monovalent ions had no effect.
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Clarkson et al. (1961) studied this question.