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May 13, 2023TrialsOpen Access

Cardiovascular implications and physical activity in middle-aged and older adults with a history of COVID-19 (CV COVID): a protocol for a randomised controlled trial

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Why the study?

It is not fully understood to what extent COVID-19 impacts cardiovascular function in the short- and long-term following infection.

Does a 12-week home-based physical activity intervention improve left ventricular global longitudinal strain in middle-aged and older adults with a history of COVID-19?

Population

120 vaccinated adults aged 50 to 85 years, including 80 with COVID-19 history and 40 controls

Comparison

12-week home-based physical activity intervention vs control among participants with a history of COVID-19

Design

Prospective, single-centre randomised trial protocol

Follow-up

12-week

Authors

MRMushidur RahmanHealth & Life (Taiwan)SRSophie L. RussellHealth & Life (Taiwan)NONduka C. OkwoseHeart Failure & Transplant

Discussion

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Implication

Post-COVID arterial stiffening, especially in women; leaves open whether it raises event risk or warrants monitoring.

Structured PICO

Does a 12-week home-based physical activity intervention improve left ventricular global longitudinal strain in middle-aged and older adults with a history of COVID-19?

P
Population
120 COVID-19-vaccinated adults aged 50-85 years, including 80 with a history of COVID-19 and 40 healthy controls without a history of COVID-19. Excludes individuals with known chronic respiratory or cardiovascular conditions, severe hypertension, BMI > 35 kg/m2, or those previously ventilated during COVID-19 infection.
I
Intervention
12-week home-based physical activity intervention aiming to increase daily steps by at least 2000 steps per day from baseline, monitored via pedometer and supported by weekly telephone calls.
C
Comparator
Control group provided with a pedometer to record daily step count but not instructed to increase daily step count.
O
Outcome
Mean change in left ventricular global longitudinal strain after 12 weeks of the study intervention.surrogate

This study protocol outlines a randomized controlled trial to evaluate whether a 12-week home-based physical activity intervention improves cardiovascular function, specifically left ventricular global longitudinal strain, in adults with a history of COVID-19.

Cite This Study

Rahman et al. (2023) studied this question.

synapsesocial.com/papers/6a7245752163a0a01bc6064ahttps://doi.org/10.1186/s13063-023-07360-7

Topics

COVID-19 cardiovascular
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