Why the study?
Does plasma 18-hydroxycorticosterone concentration distinguish aldosterone-producing adenomas from hyperplasia in patients with primary aldosteronism?
Population
23 patients with primary aldosteronism
Comparison
Measurement of plasma 18-hydroxycorticosterone… vs Aldosterone-producing adenomas versus hyperplasia
Design
Cross-sectional
Authors
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May aid subtype differentiation in primary aldosteronism; leaves open prospective validation before clinical adoption.
Does plasma 18-hydroxycorticosterone concentration distinguish aldosterone-producing adenomas from hyperplasia in patients with primary aldosteronism?
Plasma 18-hydroxycorticosterone is an effective biomarker for distinguishing aldosterone-producing adenomas from hyperplasia in patients with primary aldosteronism.
Biglieri et al. (1979) studied this question.
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