Answers are grounded in this paper and cite their sources.
A method is described for the detection of slow breakdown reactions that sometimes occur in chromatographic columns. Hydrolysis of lecithin on aluminum-oxide columns has been demonstrated to occur under conditions normally used in the chromatography of phosphatides. About 1% of lecithin is estimated to be destroyed on alumina columns in 1 hour at 22°. A substantial part of the decomposed lecithin is found as lysolecithin. Lowering the working temperature to 2° markedly reduces the rate of the degradation of lecithin and that of the formation of lysolecithin.
No takes yet. Share an insight, caveat, or question.
O. Renkonen (1962) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: