Unlike many solid tumors which present as a single mass, prostate cancer is usually multifocal and more difficult to detect.1 Additionally, prostate cancer symptoms do not typically present until the cancer has reached an advanced stage.2 As a result, physicians have consistently relied on biomarkers as indicators of the presence and progression of cancer; an ideal biomarker would allow the physician to determine cancerous tissue from non-cancerous, and perhaps even metastatic cancer from localized.
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Baum et al. (2010) studied this question.
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