Thrombolytic therapy can successfully treat superior vena cava syndrome complicating two-chamber pacemaker implantation.
Thrombolysis may be effective for pacemaker-related SVC syndrome; hypothesis-generating case report requiring prospective validation.
A 75-year-old man was admitted to our hospital because of swelling of the face and neck 6 months after implantation of a two-chamber pacemaker. Digital subtraction angiography showed total occlusion of the superior vena cava vein and well-developed collateral channels. After thrombolytic therapy, facial swelling disappeared. Digital subtraction angiography performed after thrombolytic therapy revealed a recanalization of the superior vena cava.
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Murakami et al. (1990) studied this question.
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