Why the study?
Are epicardial fat thickness and neutrophil to lymphocyte ratio associated with a non-dipper blood pressure pattern in hypertensive patients?
Are epicardial fat thickness and neutrophil to lymphocyte ratio associated with a non-dipper blood pressure pattern in hypertensive patients?
Epicardial fat thickness and neutrophil to lymphocyte ratio are independently associated with a non-dipper blood pressure pattern, suggesting a link between visceral adiposity, systemic inflammation, and impaired circadian blood pressure variation.
BACKGROUND: In this study, we aimed to investigate the relationship between echocardiographic epicardial fat thickness (EFT), neutrophil to lymphocyte ratio (NLR; an important inflammatory marker), and diurnal blood pressure (BP) changes in patients with recently diagnosed essential hypertension. METHODS: A total of 647 patients underwent echocardiography and 24 hours of ambulatory BP monitoring. EFT was measured by echocardiography, while NLR was measured by dividing the neutrophil count by the lymphocyte count. Patients were categorized into three groups according to BP pattern: the normotensive group, the dipper group, and the non-dipper group. CONCLUSION: EFT and NLR are independently associated with impaired diurnal BP profiles in hypertensive individuals. EFT (as measured by echocardiography) and NLR appear to be helpful in stratifying cardiometabolic risk.
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Kim et al. (2016) studied this question.
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