Visceral Larva Migrans Associated with the Hypereosinophilic Syndrome and the Onset of Severe Asthma

Brief Reports15 May 1992Visceral Larva Migrans Associated with the Hypereosinophilic Syndrome and the Onset of Severe AsthmaGregory J. Feldman, MD, H. Worth Parker, MDGregory J. Feldman, MD, H. Worth Parker, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-116-10-838 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptVisceral larva migrans, a syndrome with various clinical manifestations, is infrequently recognized. In the United States, the parasite responsible for most visceral larvae migrans is the common roundworm of the dog,Toxocara canis. With few exceptions, the visceral larva migrans syndrome has been recognized mainly in children 1 to 4 years of age, and is characterized primarily by hepatomegaly with fever, leukocytosis, persistent eosinophilia, and hypergammaglobulinemia (1-3). Although rare case reports have described an illness with mild pulmonary involvement among adults, suggestive of visceral larva migrans (4, 5), severe bronchospasm resulting in respiratory failure has not been reported. We report...References1. BeaverSnyder PC. Chronic eosinophilia due to visceral larvae migrans: report of three cases. Pediatrics. 1952;9:7-19. MedlineGoogle Scholar2. Snyder C. Visceral larvae migrans: ten years' experience. Pediatrics. 1961;28:85-91. Google Scholar3. Mok C. Visceral larvae migrans: a discussion based on review of the literature. Clin Pediatrics. 1968;7:565-73. CrossrefMedlineGoogle Scholar4. GlickmanMagnavalDomanskiShofeitLauriaGottstein LJLFSB. Visceral larva migrans in French adults. A new disease syndrome? Am J Epidemiol. 1987;125:1019. CrossrefMedlineGoogle Scholar5. Diaz RiveraPonsRamirez REE. Pulmonary eosinophilia: Preliminary report on 15 cases of tropical eosinophilic asthma. Bol Asoc Med Puerto Rico. 1950;42:197. MedlineGoogle Scholar6. Faulkner L. Dimensions of the pet population problem. J Am Vet Med. Assoc. 1975;166:477-8. MedlineGoogle Scholar7. SchantzGlickman PL. Toxocaral visceral larva migrans. N Engl J Med. 1978;298:436-9. CrossrefMedlineGoogle Scholar8. AreanCrandall VC. Toxocariasis. The Pathology of Protozoal and Helminthic Diseases with Clinical Correlation. Edited by RA Marcial-Rojas. Baltimore: Williams & Wilkins; 1971:808-42. Google Scholar9. ChurgStrauss JL. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa, Am J Pathol. 1951;27:277. MedlineGoogle Scholar10. GlickmanSchantzDombroskeSypeff LPRR. Evaluation of serodiagnostic tests for visceral larva migrans. Am J Trop Med Hyg. 1978;27:492-8. CrossrefMedlineGoogle Scholar11. KameyaHayakawaKameyaWatanabe STAT. Hyperamylasemia in patients at an intensive care unit. J Clin Gastroenterol. 1986;8:438-42. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Gregory J. Feldman, MD; H. Worth Parker, MDAffiliations: From Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. For current author addresses, see end of text. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byToxocariasisEvidence for Asthma in the Lungs of Mice Inoculated with Different Doses of Toxocara canisTOXOCARIASIS - WHAT DO WE KNOW?Zoonotic Helminth Diseases in Dogs and Dingoes Utilising Shared Resources in an Australian Aboriginal CommunityMore bark than bite: Comparative studies are needed to determine the importance of canine zoonoses in Aboriginal communities. 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