Population
6 Langendorff-perfused sheep hearts
Design
Preclinical
Authors
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Transient wavelets from breakup challenge multiple-wavelet theory in this model; hypothesis-generating for AF drivers, needs in vivo confirmation.
In an isolated sheep heart model, multiple wavelets during atrial fibrillation are short-lived and appear to result from the breakup of high-frequency organized waves, suggesting they are not the primary mechanism for AF maintenance.
J Chen (2000) studied this question.
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