Why the study?
Studies examining the efficacy of controlling blood pressure and inhibiting the renin-angiotensin system in preventing CKD progression are limited.
Does alisol B 23-acetate attenuate renal fibrosis and hypertension in rat models of chronic kidney disease?
Does alisol B 23-acetate attenuate renal fibrosis and hypertension in rat models of chronic kidney disease?
Alisol B 23-acetate attenuates chronic kidney disease progression and hypertension in rat models by regulating the renin-angiotensin system and gut microbiome.
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ABA may attenuate CKD progression via microbiome-RAS effects in rats; leaves open human translation.
Chen et al. (2020) studied this question.
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