Why the study?
Does continuous epidural anesthesia with bupivacaine and fentanyl alter intrapartum fetal heart rate tracings compared to bupivacaine alone in women with uncomplicated pregnancies at term?
Does continuous epidural anesthesia with bupivacaine and fentanyl alter intrapartum fetal heart rate tracings compared to bupivacaine alone in women with uncomplicated pregnancies at term?
Answers are grounded in this paper and cite their sources.
The addition of fentanyl to bupivacaine for continuous epidural anesthesia during labor does not obscure or significantly alter fetal heart rate tracings.
OBJECTIVE: To evaluate the effect of narcotic and non-narcotic continuous epidural anesthesia on intrapartum fetal heart rate (FHR) tracings as measured by computer analysis. METHODS: We studied 37 women with uncomplicated pregnancies at term with reactive FHR tracings. The women were randomized to receive epidural anesthesia with either bupivicaine with fentanyl or bupivicaine alone. One-hour FHR tracings were obtained before epidural anesthesia. Thirty minutes after the initial bolus of the epidural a repeat computer analysis of 60-minute FHR tracing was obtained. Median values are reported for FHR parameters with statistical analysis performed by the Mann-Whitney U and Wilcoxon signed rank tests where appropriate. A power calculation was performed using a power of 90% to determine a required sample size of 28 patients. Statistical significance was set at P < .05. RESULTS: In early first stage of labor, there was no significant difference in pre- and postepidural anesthesia FHR baseline, accelerations of 10 and 15 beats per minute, episodes of high and low variation, and short- and long-term variation when using either narcotic or non-narcotic anesthetic agents. CONCLUSIONS: Thus, the clinician can consider the use of narcotic as well as non-narcotic continuous epidural anesthesia in the dosages used in our study with its attendant advantages without fear of obscuring the fetal heart rate tracing.
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Hoffman et al. (1997) studied this question.
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