Transient parkinsonism associated with alcohol intake and withdrawal has previously been described. We followed-up three patients with acute alcohol withdrawal-induced parkinsonism 9-11 years after their initial presentation. None showed any evidence of parkinsonism at follow-up. This suggests that withdrawal-induced parkinsonism is caused by a completely reversible abnormality in nigrostriatal dopamine transmission, which is unaccompanied by underlying nigral degeneration, as we had previously hypothesized.
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Shandling et al. (1990) studied this question.
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