Investigates telomere length predicting outcomes in prostate cancer, suggesting implications for therapy.
Summary: The combination of variable telomere length in cancer cells and shorter telomere length in cancer-associated stromal cells strongly correlates with progression to prostate cancer metastasis and cancer death. The implication is that telomere length measurements have potential not only as prognostic indicators of prostate cancer outcomes but also as risk stratification enrichment biomarkers for individualized therapeutic interventions. Cancer Discov; 3(10); 1096–8.
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Jerry W. Shay (2013) studied this question.
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