June 6, 2007Journal of Cardiovascular Electrophysiology

Time to Electrode Rewarming After Cryoablation Predicts Lesion Size

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Why the study?

Does time to electrode rewarming predict lesion size during cryoablation in a porcine model?

Population

Live porcine left ventricle in a saline bath (37 degrees C), N=80 experiments

Design

Preclinical

Authors

BPBabar ParvezVanderbilt University SGS. GoldbergHadassah Academic College VPVishesh PathakVirginia Commonwealth University

Discussion

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Implication

May refine preclinical cryoablation parameters; leaves open translation to human lesion prediction and outcomes.

Structured PICO

Does time to electrode rewarming predict lesion size during cryoablation in a porcine model?

Population

Live porcine left ventricle in a saline bath (37 degrees C), N=80 experiments

Intervention

Cryoablation for 300 seconds using an 8-mm-tip catheter under permutations of electrode orientation (vertical or horizontal), contact pressure (6 or 20 g), and superfusate flow over electrode-tissue interface (0.2 or 0.4 m/s)

Outcome

Lesion volume prediction by time to rewarm to +30 degrees C, time to cool to -75 degrees C, and electrode temperaturesurrogate

Time to cryoablation electrode rewarming is a better predictor of lesion size than electrode temperature in a preclinical model.

Cite This Study

Parvez et al. (2007) studied this question.

synapsesocial.com/papers/6a72884ea528af2d65c473c5 https://doi.org/10.1111/j.1540-8167.2007.00871.x

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Time to Electrode Rewarming After Cryoablation Predicts Lesion Size

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Time to Electrode Rewarming After Cryoablation Predicts Lesion Size

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider