This case report highlights that metastatic liposarcoma can lead to pulmonary venous tumor thrombosis and lung infarction, a complication not previously described for this disease.
Recognize possible tumor thrombosis and infarction in metastatic liposarcoma; extends known complications but remains hypothesis-generating.
Pulmonary vein thrombosis has been described in several patients including those with malignancy, pulmonary veno-occlusive disease, fibrosing mediastinitis, and after lung transplantation. 1-5 Although liposarcoma frequently metastasizes to the lungs, to our knowledge pulmonary venous (tumor) thrombosis with lung infarction has not been previously mentioned as part of this disease. We report a case of liposarcoma with pulmonary metastases with secondary pulmonary venous (tumor) thrombosis and infarction, presenting 3 years after diagnosis of the original tumor.
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Tamizifar et al. (2012) studied this question.
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