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November 15, 2007Virology JournalOpen Access

Genetic characterisation of the recent foot-and-mouth disease virus subtype A/IRN/2005

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Population

Foot-and-mouth disease virus subtype A/IRN/2005 isolates

Design

Preclinical

Authors

JKJörn KleinNorwegian University of Science and TechnologyMHManzoor HussainKarakoram International UniversityMAMunir AhmadNingbo University

Discussion

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Implication

Supports vigilant FMDV surveillance in livestock; leaves open functional impacts of recombination on vaccine efficacy.

Structured PICO

P
Population
Foot-and-mouth disease virus subtype A/IRN/2005 isolates (3 complete coding sequences from Pakistan, 1 from Turkey, and partial 1D coding sequences from 4 epithelium and 34 swab samples from Asian buffaloes or cattle)
I
Intervention
Genetic sequencing and phylogenetic analysis
O
Outcome
Phylogenetic relationships and evolutionary paths of structural and non-structural genome regions

Genetic characterization of the A/IRN/2005 foot-and-mouth disease virus reveals distinct evolutionary paths for structural and non-structural genome regions, including potential recombination events.

Cite This Study

Klein et al. (2007) studied this question.

synapsesocial.com/papers/6a729dd2439bab0cabc3e2b8https://doi.org/10.1186/1743-422x-4-122
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Distinct repertoire of antigenic variants of foot-and-mouth disease virus in the presence or absence of immune selection1993 · 121 citations
  2. 2Unapparent foot and mouth disease infection (sub-clinical infections and carriers): implications for control2002 · 92 citations
  3. 3Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate1996 · 372 citations
  4. 4The molecular epidemiology of Foot-and-Mouth Disease virus serotypes A and O from 1998 to 2004 in Turkey2006 · 42 citations
  5. 5Mosaic structure of foot-and-mouth disease virus genomes2007 · 63 citations