Why the study?
Cardiovascular diseases are the primary cause of death in women, and the accuracy of currently available risk scores remains questionable.
Does incorporating family history, exercise testing variables, and subclinical atherosclerosis markers improve cardiovascular risk reclassification compared to the Framingham Risk Score alone in asymptomatic middle-aged women?
Does incorporating family history, exercise testing variables, and subclinical atherosclerosis markers improve cardiovascular risk reclassification compared to the Framingham Risk Score alone in asymptomatic middle-aged women?
Incorporating family history, exercise testing, and subclinical atherosclerosis markers may help reclassify cardiovascular risk in asymptomatic middle-aged women beyond the traditional Framingham Risk Score.
May refine FRS stratification in asymptomatic women; leaves open whether reclassification improves outcomes or warrants practice changes.
Background Cardiovascular diseases are the main cause of death in women and the accuracy of currently available risk scores is questionable. Objective To reclassify the risk estimated by the Framingham Risk Score (FRS) in asymptomatic middle-aged women by incorporating family history, exercise testing variables, and subclinical atherosclerosis markers. Methods This cross-sectional study included 509 women (age range, 46-65 years) without cardiovascular symptoms. Those at low or intermediate risk by the FRS were reclassified to a higher level considering premature [...]
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Coutinho et al. (2021) studied this question.
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