Why the study?
Does methylprednisolone and azathioprine restore normal atrioventricular conduction in a patient with complete AV block and anti-Ro52 antibodies?
Does methylprednisolone and azathioprine restore normal atrioventricular conduction in a patient with complete AV block and anti-Ro52 antibodies?
Immunosuppressive therapy with methylprednisolone and azathioprine may reverse complete atrioventricular block in patients with anti-Ro52 antibodies.
May support immunosuppression trial in anti-Ro52 AV block; leaves open efficacy and generalizability.
Complete atrioventricular block developed in a 26-year-old woman, and she was found to have antinuclear antibodies, including antibodies against Ro52. Treatment with methylprednisolone and azathioprine restored normal atrioventricular conduction.
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Bai et al. (2013) studied this question.