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This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and the potential adverse effects, including cancer, of folate supplementation, either in folic acid form or in 5‐methyltetrahydrofolate form, alone or in combination with other micronutrients, on folate status and health outcomes (physical, psychological, and neurocognitive) among women of reproductive age.
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Tsang et al. (2015) studied this question.
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