Peripheral Ossifying Fibroma: Series of Three Cases

Peripheral ossifying fibroma (POF) is a reactive soft tissue growth that predominantly affects females and usually seen on the interdental papilla. Its color ranges from pale pink to cherry red, and it might have a smooth surface or a broad base with pedunculation. This study’s purpose is to evaluate and compare three different POF cases with histopathological and radiological examination. Two female and one male patients of different ages came to our clinic with a complaint of asymptomatic, soft tissue growths in the anterior region of the interdental papillae area. The lesions were surgically excised and sent for histopathological examination which confirmed the diagnosis of POF. Even though the etiology of the POF is unclear, trauma or local irritation such as plaque, calculus, ill-fitting dental appliances, and poor-quality dental restorations are all known to precipitate the development of POF. Dentists should consider clinical differential diagnoses such as pyogenic granuloma, fibroma, and peripheral odontogenic fibroma.