Key result
Immediate lifestyle intervention significantly improves weight loss and cardiometabolic risk factors versus delayed control.
RCT (n=134)
Randomized to immediate vs. 6-month delayed control intervention
Yes
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Purpose The purpose of this study is to evaluate the feasibility and effectiveness of an adapted Diabetes Prevention Program (DPP) lifestyle program, DPP Group Lifestyle Balance (GLB), delivered in 3 economically diverse senior/community centers. Methods The DPP-GLB was implemented in 3 senior/community centers in Allegheny County, PA. A 6-month delayed control intervention design was used. Participants were randomized to begin the DPP-GLB immediately (immediate) or after a 6-month delay (delayed). Adults (n = 134; mean age = 62.8 years) with BMI ≥24 kg/m 2 and prediabetes and/or the metabolic syndrome took part. Weight, physical activity (PA), and diabetes and cardiovascular disease (CVD) risk factors were assessed at 6, 12, and 18 months from baseline. Results At 6 months, the immediate group demonstrated greater mean weight loss than the delayed control group as well as significantly greater improvements in PA, A1C, fasting insulin, and waist circumference. In pre-post analyses, both randomized groups showed similar success that was maintained at 18 months. Conclusions The DPP-GLB delivered in economically diverse community centers was effective in this group of older adults. These findings support provision of coverage for prevention programs in older adults at risk for diabetes/CVD, which is important considering the large number of individuals who will be Medicare eligible in the near future.
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Kramer et al. (2018) conducted an RCT in Prediabetes and/or metabolic syndrome (n=134). Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB) immediate intervention vs. 6-month delayed control group was evaluated on Weight loss, physical activity, and diabetes and cardiovascular disease risk factors (A1C, fasting insulin, waist circumference) at 6 months. Immediate DPP-GLB lifestyle intervention resulted in significantly greater weight loss and improvements in PA, A1C, fasting insulin, and waist circumference at 6 months vs. delayed control (n=134).
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