Structure-Based Design of Novel Bicyclic Nonpeptide Inhibitors for the Src SH2 Domain

ADVERTISEMENT RETURN TO ISSUELetterNEXTStructure-Based Design of Novel Bicyclic Nonpeptide Inhibitors for the Src SH2 DomainWilliam C. Shakespeare, Regine S. Bohacek, Mihai D. Azimioara, Karina J. Macek, George P. Luke, David C. Dalgarno, Marcos H. Hatada, Xiaode Lu, Shelia M. Violette, Catherine Bartlett, and Tomi K. SawyerView Author Information ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, Massachusetts 02139-4234 Cite this: J. Med. Chem. 2000, 43, 21, 3815–3819Publication Date (Web):September 28, 2000Publication History Received2 August 2000Published online28 September 2000Published inissue 1 October 2000https://pubs.acs.org/doi/10.1021/jm0003337https://doi.org/10.1021/jm0003337rapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views539Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Amines,Hydrophobicity,Molecules,Peptides and proteins,Phenyls Get e-Alerts