The effect of the methanol fraction of Pluchea indica (P. indica) and certain standard drugs were evaluated on platelet activation factor (PAF)-induced inflammation, gastric necrosis, ulceration and haematological picture. Administration of PAF (i.v.) for 20 min produced significant alteration in haematological profiles, considerable inflammation, severe gastric mucosal vasocongestion, necrosis and ulceration. Pretreatment with either P. indica and certain standard drugs significantly inhibited inflammation and incidences of lowered gastric damage.
No takes yet. Share an insight, caveat, or question.
Sen et al. (1996) studied this question.